Zuniga began her film career with Rob Reiner’s “The Sure Thing” with John Cusack. Then, a childhood dream came true when she was cast opposite Lucille Ball in Ball’s final performance, “Stone Pillow”.

Daphne went on to star in feature films such as Mel Brooks’ “Spaceballs”, “Vision Quest”, “Gross Anatomy” both with Matthew Modine, Other films include, “Staying Together” “Last Rights” and “Stand Ins”.

Zuniga then became familiar to millions of viewers as Jo Reynolds on the hit series “Melrose Place.”

From the ultra sexy centerfold Shelly Pierce on the NBC series “American Dreams,” Daphne went on to star on the ABC Family series “Beautiful People” and then with Jay Mohr in the ABC Family film, “Christmas Everyday”.

2010 saw Daphne star in and produce the Hallmark movie “A Family Thanksgiving”, with Academy Award winner Faye Dunaway. Here she got to show off her comedic side, when she plays a single high-powered attorney, who suddenly finds herself in an alternate reality as a mom, juggling carpool and diapers. She then finished off the year starring in the highly rated Lifetime Movie “On Strike for Christmas”.

After playing the icy Victoria Davis on CW’s “One Tree Hill” for five years, Daphne starred in Lifetime’s “Gone Missing”, the two films, “Beyond Paradise” and “A Remarkable Life” to be released in 2014, and she will make an appearance in the film “Who’s Driving Doug” Starring RJ Mitte as her son.

In 2015 Daphne appeared in VH1’s new show Hindsight and filmed indie Those Left Behind, TV movie When Duty Calls and Relativity’s digital musical feature Summer Forever. She is developing a half hour comedy to star in.

Born in Northern California and raised between there and Vermont, Zuniga is the eldest daughter of a Unitarian minister mother, and a philosophy professor father. Daphne studied a year at the American Conservatory Theater in San Francisco before attending UCLA. She studied with renowned acting teachers, Peggy Feury at the Loft Studio, Larry Moss, and Penny Allen.

Devoted to the environment, Daphne was appointed by Los Angeles Mayor Villaraigosa to the founding Board of the LA River Revitalization Corp. ( Her documentary of the TED Conference “The Future We Will Create,” which she produced and directed, is currently available on Netflix, and Amazon.

Environmental Awards: Children’s Nature Institute, California League of Conservation Voters, Barcelona International Environmental Film Festival